SIRE Life Sciences

 

Gegevens

Adres
Herengracht 466
Spiegelhof
Postcode 1017 CA
Stad Amsterdam
Land Nederland
Telefoonnummer +31 (0) 20 658 9800
Email info@sire-search.com
  • Mechatronics Architect

    3 dagen geleden

    SIRE Information Technology ® - Friesland

    Use your engineering expertise to model, design and implement new domestic appliances products. Your contribution can range from early marketing and sales contacts for user requirements, Principal Architects support to project definition and concept creation of electromechanical functions, system layout, requisite mapping, and mechatronics interfaces definition. Responsibilities You will be directly responsible for the overall design of the electromechanical architecture in a large platform definition project, which has a long-term character, complex, and divided in several sub-projects for the creation of subsystems. This also requires involvement in software and electronic hardware designs, together with multi-disciplinary teams of highly skilled technical experts. You contribute in defining the electromechanical architecture, modules interfacing, and introduction of new technology and methods, directly reporting to the Principal Platform Architect, IPLs (Integral Project Leaders), and to Pre-development and Electronic & Software team leaders. You will be supported by mechanical, mechatronics, hardware and software specialists for the efficient and correct integration of existing platform building blocks, and for defining requirements, development steps and validation process of all new functions.
    1 broker
  • Electronic Data Maintenance and Transfer Specialist

    5 dagen geleden

    SIRE Information Technology ® - Noord-Brabant

    As the Electronic Data Maintenance and Transfer Specialist, you are responsible to manage the lifecycle of electronic (including related mechanical) hardware data (integrity, status, transfer, obsolescence). You will work with a team of electrical, mechanical engineers, and manufacturing engineers to ensure that Technical Product Data (TPD), used for describing and creating hardware is transferred to suppliers and sub-contractors. This data needs to be managed by a professional Electronic Data Maintenance and Transfer Specialist to control the content, format, integrity and lifecycle. You are responsible for these aspects of the data on electronics and assemblies of electronics in cabinets. Second focus area will be on ensuring production continuity by driving from start to end supplier change requests and find solutions for end of life of electronic components. Final focus area will be on leading a dual sourcing project which scope is to identify and release second sources for E-components. Responsibilities Key areas of responsibility:  Check integrity of CAD-E and associated assemblies and CAD-M data o Check data before transfer on correctness and completeness o Approver in Agile for electronic DMR.  Transfer to suppliers: Exchange data with suppliers  Communication person between our client and supplier about DMR issues.  Consulting on applicable standards, tools and assembly processes o Main contacts are with (senior) developers and designers of electronic circuits, designers of programmable logic and designers of cabinets, cables and mechanical sub-assemblies as well as with suppliers of electronic components, PCBA’s and electronic sub-assemblies.  Manage lifecycle of components o Once a month EOL meeting with more BU’s about eol Neways components. o Obsolescence: He actively collects this data and initiates the necessary actions to optimize consequences for the products these components are used in or on. o Dual sourcing: ensure dual sourcing is in place for key electronic components o Dual sourcing team 2 engineers and other people from Component management. o Do proactive scanning on PCBA’s when will components be EOL with CPM.  Improvement proposals: Learning from current way of working propose improvements  Support: General support to development groups in Best regarding TPD and technical issues  Other activities: o Actual assembly of PCBA data for transfer to supplier (‘Sam zak’). o Suggest process improvements for data integrity incl. ECR and EoL, data transfer and data storage. o Assist low-frequent users in data transfer and archiving. o Assist in CAD-E tool validation. o Assist in qualifying component, PCBA and assembly suppliers. o Preparation of sam zak(in zip format) for quotes, including description for use. o Consultancy on technological solutions used at potential supplier. o Based on specific EoL signal, create relevant ECR, cf. next bullet. o Consultant in EoL solutions: e.g. advice on business driven choice between EoS, redesigns, last-time-buy and rework service parts alternatives.
    1 broker
  • Senior Packaging Buyer

    1 week geleden

    SIRE Life Sciences ® - Noord-Holland

    You will manage mainly the laminates portfolio within Europe in all business aspects across different divisions within the company. They key focus is on finding the synergies, co-building and executing the strategies as well as contributing to packaging policy implementation in aspects of innovation and sustainability. Responsibilities Part of your responsibilities will be: • Connect inside and outside of the organization to ensure the supply security, new sources identification, support quality compliance and drive the sustainability agenda in line with Packaging team ambition. • Contribute to deliver productivity targets through timely execution of the projects in the nominated category and region. • Supplier relationship management, conducting negotiation, price model’s implementation, MRM updates, timely price-lists agreements and submission for the contract team • Price discrepancy management, ensuring compliance • Reporting and updating the deliverables across flexibles packaging for the nominated categories in Europe • Support the global Packaging team in data management, rolling forecast management, budgeting • Driving the optimization and implementation of functional specifications, optimizing run-sizes and print technologies to fulfil consumer demands better • On top you will be a single point of contact for one of our most dynamic divisions – Specialized Nutrition (SN), in this mission you will be responsible for (but not limited with): o Representation of the Packaging team within key SN forums o Driving laminates sourcing agenda within Europe (RFQ; prices; supply security; sustainability; quality etc.) and co-building sourcing strategies to support product development and operations strategy execution within SN o Delivering the key objectives related to laminates projects execution on behalf of Packaging team, SRM to support timely projects’ execution and deliverables • You will add value by providing examples for synergies across divisions and use these to drive the teams to successful implementation, fast and qualitatively
    1 broker
  • Specialty Ingredients Buyer | Start 01/09/19 | Freelance | 5 months | Amsterdam Area

    2 weken geleden

    SIRE Life Sciences ® - Noord-Holland

    As specialty Buyer you have a key position delevering innovative, efficient and sustainable sourcing to reacht the 3 missions around People, Profit and Purpose Responsibilities - Develop in depth market knowledge on players and insights including business needs - Co-decelop and activate sourcing strategy with the global category teams and onther stakeholders involved: Procurement teams, R&D, Operations and Quality - Manage and lead Supllier Network - Identify, Build and develop Supplier relationship with local and global suppliers in the regions in line with objectives set by the global category strategy - Preparation of performance objectives and annual business reviews - Identify key innovation needs with Marketing and R&D, particularly in early stages of developments - Leverage supplier network and asses innovation capabilities - Support the central procurement team to deliver productivity and innovation project - Prepare or contribute to Budget, Price lists and Material Variance Analysis - Monitor Financial performance: productivity & cash - Ensure supplier Qualit compliance: Manufactering site audit, Sedex - Support contract compliance & GTCP's - Support and ensure that factory material demand is met - Support Business Contingency plans on critical materials - Improve forecast accurancy with demand planning and Suppliers - Implement Serivice level agreement with suppliers: On Time In Full Deliver
    1 broker
  • Mechanical Electronical Technician - Temporary

    2 weken geleden

    SIRE Life Sciences ® - Noord-Holland

    You will be part of a newly formed team, in which employees from different backgrounds and experiences are respected. You contribute to saving lives on a daily basis. Partly because of your work, patients can rely on a medicine that has been produced in the right way. You will be part of the structure of the Engineering & Facility organization and the associated systems and will report to the Maintenance & Calibration manager. Responsibilities As a Mechanical Engineering Technician you are responsible for the repair and maintenance of facilities, mechanical installations and related equipment. In this role you are responsible for the technical condition of the building-related equipment such as HVAC, utilities and other mechanical systems. You support the new innovative biotechnology facility in the Amsterdam region with general bio-processing laboratories. Responsible for the repair and maintenance of mechanical installations, equipment and related equipment of the pharmaceutical site. Supervise and monitoring work performed by external parties - Follow-up and permanent correction of disruptions in the Mechanical Utilities - Document the work performed in accordance with cGMP guidelines. - Supports the development of guidelines and standards for mechanical engineering - Able to work in 2 shifts and / or to operate on-call breakdown services.
    1 broker
  • Electrical Engineer

    2 weken geleden

    SIRE Information Technology ® - Zuid-Holland

    Provide technical support in the design, installation, testing, and start-up for a variety of industrial control systems. design, develop and assemble electrical or electrical-mechanical modules for system. Responsibilities - Researches products and devices from conceptual concepts, designs, develops, and tests the electrical/electronic aspects of processing equipment according to established policies, procedures, government regulations, and customer requirements; - Generates conceptual designs and determines feasibility of the designs; - Builds prototypes; works with the lab to develop test fixtures of conceptual designs; - Documents specifications and material requirements on all designs; - Troubleshoots advanced malfunctions and other unusual problems; - Ensures adherence to established project schedules and priorities; - Assists other to ensure schedules and priorities are met; - Follows up and supports complex electrical and electronic designs in research and development, manufacturing, and the field; - Leads in the compliance and safety testing of various electrical systems for regulatory agencies.
    1 broker
  • Facility Engineer

    2 weken geleden

    SIRE Information Technology ® - Zuid-Holland

    In this role you'll supervise and direct all aspects for the operation, maintenance, repairs, and improvements to facilities and facilities services and buildings, including all equipment and machinery of the utility systems. Complies with Good Manufacturing Practice and Safety and Environmental Regulations to ensure execution, compliance, and proper reporting. Ensure compliance with facilities standards as defined by the company and External Governmental bodies. Responsibilities - Manages Facilities and Facilities services according to GxP and EHS regulatory requirements; assures change implementation complies with local and federal regulations; evaluates impact and actions plan to assure proper implementation; - Ensures the service activities performed by the Facilities partner in the areas of responsibility to comply with production requirements and standardization expectations. Ensures the repair, installation, and maintenance of facility systems are conducted according to the established requirements and in compliance with applicable regulations. Supervises and/or oversees in-house and subcontracted jobs in the area of responsibility to ensure compliance with the established requirements and company policies, as applicable; - Develops key performance indicators aligned with regulatory requirements; reports periodically to management. Develops and completes an action plan to assure key performance indicators are maintained in control; - Identifies issues and risks that can cause failure to comply with any EHS and quality regulatory requirement, downtime or impact the financial plan; report to management, providing alternatives to assure issues or risks are mitigated; - Keeps standard operational procedures of the area updated and assures strict compliance to them; - Acts as Facilities subject matter expert for: area improvements, deviations evaluations, regulatory audits, and capital justification; - Supports major process and facilities projects, including conducting project team meetings; - Actively participates in the strategic plans development for business operations; - Ensures the establishment, implementation, execution, and monitoring of the facilities environmental controls throughout the facilities maintenance system; - Ensures compliance with environmental legal requirements; manages EHS and Quality improvement plans as per site CAPA system; - Adopts and deploys EHS systems ownership through the facilities team; - Ensures the establishment, implementation, monitoring, and the maintenance of the environmental management systems; - Assures compliance with applicable legal requirements; - Develops environmental objectives and targets and promotes and encourages employees to achieve these objectives and targets; - Assures trainings in the assigned tasks have been delivered prior to execution; - Acts in accordance to the principles expressed in Our Credo and the Quality Statement in all negotiations and activities within and outside the company and assures these are met; - Develops, administers, and controls assigned budget to maximize utilization, reduces operational costs, and complies with corporate standards; - Prepares performance reports on accomplishments and situations of the area for the department head.
    1 broker
  • Global Lead Utility Engineering

    2 weken geleden

    SIRE Information Technology ® - Zuid-Holland

    We are looking for a Global Lead Utility Engineering with in-depth knowledge of sustainable (brewery) utilities. Responsibilities - Discuss scope and challenge investments with senior management and project managers; - Prepare project plans, inquiry specifications and purchasing specifications; - Guide, monitor and check suppliers; - Are responsible for successful handing over of utility installation to the breweries; - Participate actively in our global sustainability program “Drop the C”; - Contribute to internal projects in the fields of standardization; - Build and maintain a network of suppliers; - Execute utility surveys and advise breweries on improvements; - Monitor, guide and support a variety of external consultants under your supervision.
    1 broker
  • Machanical Engineering Technician

    2 weken geleden

    SIRE Information Technology ® - Noord-Holland

    Als Mechanical Engineering Technician ben je verantwoordelijk voor de reparatie en het onderhoud van faciliteiten, mechanische installaties en aanverwante apparatuur. In deze rol ben je verantwoordelijk voor de technische staat van de gebouw gebonden apparatuur zoals HVAC, utiliteiten en andere mechanische systemen. Je steunt de nieuwe innovatieve biotechnologie-faciliteit in de regio Amsterdam met algemene laboratoria voor bio-processing. Je zal deel uit maken van een nieuw gevormd team, waarin medewerkers van verschillende achtergronden en ervaringen worden gerespecteerd. Responsibilities Verantwoordelijk voor de reparatie en het onderhoud van mechanische installaties, equipment en aanverwante apparatuur van de farmaceutische site. Begeleiden van werkzaamheden en toezicht houden op werkzaamheden uitgevoerd door externe partijen - Opvolgen en permanent verhelpen van verstoringen in de Mechanische Utilities; - Documenteren van de uitgevoerde werkzaamheden volgens cGMP richtlijnen; - Ondersteunt de ontwikkeling van richtlijnen en normen voor werktuigbouwkunde; - In staat om in 2 ploegendienst te werken en/of on call storingsdiensten te draaien.
    1 broker
  • Maintenance Engineer Utilities & Buildings

    2 weken geleden

    SIRE Information Technology ® - Zuid-Holland

    As a maintenance engineer UB (utilities & buildings) you will deploy and coordinate utility and facility maintenance to ensure compliance with Good Maintenance and Manufacturing Practices. You will shape and improve procedures and processes, conduct preventive-, corrective- and replacement maintenance on the owned UB systems whereby the technical focus area will be primarily mechanical and electrical. Responsibilities You will be part of a multidisciplinary team of maintenance/engineering specialists in which you will: - Play a key role during the yearly maintenance shutdown period in which our GMP production facilities is handed over to EVM for extensive maintenance. You will be (sub)-lead for preparation, execution and finalization of this operation; - Serve as the Subject Matter Expert for several Utility and Building systems; - Be leading and supporting improvement and modification projects within the engineering department; - Interact with peer functions throughout the organization to provide expert knowledge to related support departments like; Operations, Automation, Process Engineering, Quality Assurance to assure efficient and reliable technical support to our customers; - Work with various control, monitoring and database systems (BMS, PLC, LMS, BMS, EFMS). Your key responsibilities: - Define, Deploy and coordinate utility and facility maintenance to ensure compliance with Good Maintenance and Manufacturing Practice for our systems including pharma grade water and steam systems, medical gases, HVAC, together with a leading electrical role; - Functions as the UB expert in our multi-disciplinary team and as UB SME during external inspections or audits; - Perform the SME role on the assigned UB systems; - First/second line troubleshooting in case of technical problems; - Planning and coordination of preventive, corrective and replacement maintenance activities; - Strategize and control the spare part control and availability; - Preparation, organization and coordination of yearly maintenance/calibration shutdown activities; - Handling of compliance records (Change controls, Events, CAPA, Deviations); - Handling of maintenance & calibration and requalification documentation in a GMP environment; - Represent maintenance/engineering in projects; - Support continuous improvement projects within EVM department; - Perform RCM on UB systems; - Lead/support improvement and modification projects on UB systems; - Member of the 24/7 support team (on duty ≈every 6 weeks).
    1 broker
  • Manufacturing Industrial Engineer

    2 weken geleden

    SIRE Information Technology ® - Noord-Brabant

    This role ensures that co-manufacturing and co-packing activities will be delivered with the best right supply solution. Responsibilities Key responsibilities: 1. Optimizing its suppliers’ performance from a supply perspective. Reviewing and challenging the supplier performance by the supply criteria. Ensuring supply security by addressing potential road blockers such as capacity, capability or equipment; 2. Initiating, supporting and delivering the supply or market driven activities. Being the supply spoke, representing all supply functions, in the new product and new activities project teams; 3. Being the voice of the customer for external manufacturing in his/ her relevant areas. Responsible to deliver innovation via co-packing and co-manufacturing solutions with excellence and in line with customers’ expectations: on time, with the right quality and cost structure.
    1 broker
  • GMP Project Engineer

    2 weken geleden

    SIRE Information Technology ® - Noord-Brabant

    Our client is looking for a GMP Project Engineer who can represent and manage the delivery of engineering and maintenance projects. The delivery of these projects will require GMP utility, facility and supporting system changes. The successful candidate must have the discipline and technical knowledge to work independently and take on responsibilities as demanded by these projects. They must investigate and deploy innovative solutions to improve the efficiency of our current installations. They must ensure procedures are followed and new systems are implemented in compliance with FDA/EMA and other regulatory requirements. They will work directly with the company's SMEs, vendors and customers to ensure regulatory (e.g. validation), business, functional and application specific requirements are met. Responsibilities - Execute projects to the company's Project Execution Plan (PEP) and meet all GMP requirements; - Ensure the highest levels of project safety; - Identify project critical paths and prioritize accordingly; - Discover and understand end-user/process requirements; translate these into user requirements specifications; - Compile all project documentation including URS/FS/HDS/FAT/SAT/TOPs; - Manage design inputs to ensure robust, testable requirements are established and accurately reflect user and safety needs; - Manage day to day project activities including permitting/method statement review etc.; - Develop and document strong rational for testing strategy, acceptance criteria, and results; - Generate, review, and/or approve protocols, reports ensuring robust documentation for regulatory adherence; - Monitor installation quality and record inspections – Comply to the company and Dutch standards; - Set up and manage communication channels – Weekly report out/Project Team Meetings; - Follows a strict handover process to allow for future system maintenance.
    1 broker
  • Financial Analyst

    2 weken geleden

    SIRE ® Finance - Zuid-Holland

    This unit responsible for performing a complete and accurate Finance & Accounting for several Dutch legal entities in a compliance environment, closely collaborating with the country tax center and the financial reporting team. Responsibilities • Financial accounting for several flows in a complex environment; • Support Management Reporting; • Ensure timely financial month-end closes; • Provide assistance with ad-hoc projects/ activities; • Support by internal / external audits; • Ensure financial and SOX compliance for US GAAP
    1 broker